"Salmon DNA” refers to a regenerative injectable skin booster based on purified polynucleotides (PN) derived from salmon sources.
These bioactive molecules do not carry genetic information and do not alter cellular DNA.
Instead, polynucleotides act as biological stimulators that support tissue repair, cellular regeneration, and long-term skin resilience.
This treatment is designed to restore compromised skin, improve elasticity, reduce sensitivity, and strengthen skin structure from within — without adding volume or altering facial contours.
Polynucleotides create a favorable biological environment within the dermis, supporting cell survival, regeneration, and recovery. They enhance fibroblast function and promote healthier skin architecture over time. This results in improved skin density, elasticity, and overall skin quality.
Polynucleotides help regulate inflammatory processes and support skin barrier repair. This makes the treatment especially suitable for sensitive, stressed, post-acne, or post-procedure skin. Skin becomes calmer, more resilient, and better protected against external stressors.
Rather than filling or lifting, polynucleotides stimulate natural collagen and elastin synthesis. Rejuvenation occurs gradually, leading to firmer, smoother, and healthier-looking skin while preserving natural facial expression and proportions.
Polynucleotide therapy is performed using superficial microinjections into the dermal layer, where key regenerative processes take place. Once introduced into the dermis, polynucleotides interact directly with skin cells, supporting fibroblast activity and stimulating natural collagen synthesis.
These bioactive molecules enhance the skin’s intrinsic repair mechanisms, increasing regenerative capacity and improving tissue quality over time. As a result, the skin becomes stronger, more resilient, and better structured from within.
Polynucleotide therapy is widely used in scar and post-acne scar management, especially when combined with procedural techniques such as subcision, where controlled mechanical release of fibrotic tissue is followed by immediate polynucleotide injection to support healing and tissue remodeling.
For overall skin quality improvement, this treatment integrates seamlessly into advanced combination protocols, including:
These multi-modal approaches are widely adopted in modern Korean aesthetic protocols, where polynucleotides play a central role in skin regeneration, repair, and long-term rejuvenation. For optimal results, polynucleotide therapy is recommended as a course and demonstrates enhanced efficacy when combined with energy-based and microneedling procedures.
Skin becomes smoother, denser, and more refined. Fine lines soften, texture improves, and overall skin quality is visibly enhanced through progressive regeneration.
Polynucleotides support faster and more effective healing after inflammatory conditions, scarring, or aesthetic procedures. Skin appears calmer, healthier, and more resilient during and after recovery phases.
The skin is deeply nourished and hydrated, resulting in a fresh, luminous appearance. Glow develops gradually from within, without heaviness, volume, or artificial effect.
Transparent pricing is tailored to your personalised plan and will be confirmed during your consultation.
Yes. Polynucleotides have strong regenerative and skin-calming properties, making them suitable for sensitive, reactive, or post-procedure skin. They support barrier repair, reduce inflammation, and improve skin tolerance when delivered with an individualized protocol.
Yes. Polynucleotide therapy is highly versatile and works exceptionally well in combination protocols. It can be safely combined with IPL phototherapy, RF microneedling, Dermapen, and other energy-based treatments to enhance skin regeneration, improve texture, and support collagen remodeling. Combination approaches allow for more comprehensive and long-lasting skin quality improvement
Yes. Polynucleotides are widely used in post-acne scar and scar-repair protocols. They are often applied immediately after procedures such as subcision, where polynucleotides support tissue healing, regeneration, and remodeling of the dermal structure. This approach helps improve skin texture, elasticity, and overall scar appearance over time.
Absolutely. Polynucleotide therapy can be performed as a standalone injectable procedure to improve skin quality, hydration, elasticity, and resilience — without adding volume or altering facial features. It is especially suitable for patients seeking natural-looking skin regeneration and long-term support.
Treatment protocols are always personalized. The number of sessions, treatment depth, and combination with other modalities depend on skin condition, treatment goals, and whether the therapy is used for regeneration, scar management, or overall skin quality improvement.
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